Ana Francisca de Borja y Doria

Ana Francisca Hermenegilda de Borja y Doria, condesa de Lemos was the wife of Peruvian Viceroy Pedro Antonio Fernndez de Castro, conde de Lemos. During his absence from the capital from June 7, 1668 to November 12, 1668, she was governor of the colony. She thus became the first female governor of the Viceroyalty of Peru.

She was born into the House of Borja . She was a distant relative of Francisco de Borja y Aragn, poet and viceroy of Peru from 1615 to 1621, and, like him, descended from Saint Francis Borgia.

Source: Wikipedia