George Hewston was appointed the 16th Mayor of San Francisco upon the death of James Otis. He was sworn in on November 4, 1875 and served until December 5, 1875.
Hewston was born in Philadelphia, Pennsylvania. He apprenticed himself to a physician and then took a medical degree from the Philadelphia College of Medicine and the University of Pennsylvania. He moved with his family to San Francisco to escape the Civil War.
Source: Wikipedia