Bad Biology

Bad Biology is a dark horror comedy film directed and produced by Frank Henenlotter and rapper R.A. the Rugged Man. It stars Charlee Danielson and Anthony Sneed as sexually unfulfilled people who are drawn together because of their mutated genitalia. It was released on DVD in the UK in 2009, and in the US in 2010. Reviews were positive.

The film has cameos by JZone, WuTang Clan affiliate Remedy, Penthouse Pet Krista Ayne, Reef the Lost Cauze, Staff Sergeant John A. Thorburn, film director James Glickenhaus, and Playboy model Jelena Jensen.Henenlotter and Thorburn wrote the script together. Henenlotter acted as director and Thorburn the producer. The two met when Thorburn recruited Henenlotter to direct a rap video. As opposed to his earlier project that were either canceled or compromised, Bad Biology allowed Henenlotter and Thorburn complete creative freedom due to Thorburns investment of funds. Danielson was dating Thorburn at the time and requested to be cast. In order to make sure she was committed, Henenlotter tried to scare off, but he was glad when she stayed with the project, as he said that she was absolutely perfect for the part. Sneed, who was cast as the male lead, found out about the project from a post on Craigslist. Sneed was initially rejected because of his physique, which Henenlotter did not think was close enough to that of a junkie. Sneed promised to lose enough weight to look the part. When he followed through and lostpounds indays, Henenlotter was impressed enough to cast him. ........

Source: Wikipedia