Nutty Professor II: The Klumps

Nutty Professor II The Klumps is a 2000 American romantic comic science fiction film directed by Peter Segal. It is a sequel to the 1996 film The Nutty Professor and stars Eddie Murphy. As in the original film, Murphy plays not only the inept but brilliant scientist, Sherman Klump, but also wearing different, but equally elaborate makeup most of Shermans family. In contrast to the previous film, subplots which are centered on his family mainly his parents occupy a substantial part of the film.

After finding success with a DNA restructuring formula in the first film, Sherman Klump has created another formula which enables those who take it to find the Fountain of Youth. He has also met and fallen in love with a colleague, Denise Gaines, who has developed a method to isolate genetic material and later becomes his fiance. Together, their work has enabled Wellman College to receive a 150 million award from a pharmaceutical firm to the excitement of Dean Richmond. Despite his good fortune, Sherman has a major problem the personality of his vanquished alter ego, Buddy Love, is still ingrained inside him and causes him to act out in the same crass manner Buddy does.After a few particularly unpleasant incidents, from Buddy kicking in, when Sherman sexually insults his own therapist trying to help him with it, then does the same thing to a woman walking a dog, and later during a toast turns around and says something completely insensitive to his father at a dinner outing in honor of him, and then when Sherman intended on proposing to Denise, but then Buddy kicks in and makes it a perverted sex request, causing Denise to become mortified against him, Sherman heads to his lab where he and his assistant Jason use Denises methodology to isolate a gene in Shermans DNA where Buddy has manifested. Determined to be rid of Buddy permanently, and in spite of Jason warning him of potentially catastrophic consequences for his health, Sherman extracts the gene with Buddys DNA from inside his body. However, he does not dispose of the genetic material and as a result, Buddy becomes a sentient being when a hair from a Basset Hound who was Shermans test subject finds its way into it and causes such a reaction. To make matters worse, Jasons suspicions prove correct when Sherman discovers that, due to the extraction, his brain cells are beginning to die. ........

Source: Wikipedia