The Shaggy Dog is a 2006 American comedy film released on March 10, 2006 by Walt Disney Pictures. It is the second remake of the 1959 film of the same name, which was first remade as a television film in 1994. Both the 1959 and 1994 features, as well as the 1976 theatrical sequel and the 1987 television sequel, had a character named Wilby Daniels transforming into an Old English Sheepdog, whereas this remake presents a character named Dave Douglas transforming into a Bearded Collie. The Shaggy Dog received negative reviews from film critics.
The greedy geneticists working for Mr. Lance Strictland Philip Baker Hall, led by Dr. Kozak Robert Downey, Jr., have stolen a 300yearold sacred dog named Khyi Yang Po a Bearded Collie from a Tibetan monastery. The scientists determine that Khyi Yang Pos genetic sequence, when isolated and put into a vaccination, invades and alters the cells and DNA of a victim.When Dave returns from work, he takes the dog out in the garage, then the dog runs to get the newspaper. The dog gives him his newspaper, but as Dave reaches for it, Khyi Yang Po bites him on the hand. The saliva goes into Daves blood and DNA, infecting him. ........
Source: Wikipedia