The Solitude of Prime Numbers Italian La solitudine dei numeri primi is a 2010 Italian drama film based on the novel of the same name by Paolo Giordano, and directed by Saverio Costanzo. The film was nominated for the Golden Lion at the 67th Venice International Film Festival.
Mattia and Alice children in 1984, teenagers in 1991 are both traumatized, and isolate themselves from the people around them.When he was a child, Mattias mentally disabled twin sister Michela goes missing whilst he was supposed to look after her. He is intelligent and becomes a successful scientist, but he sometimes cuts himself on purpose. ........
Source: Wikipedia